Chemicals and Drugs

Methylenebis(chloroaniline)

Aromatic diamine used in the plastics industry as curing agent for epoxy resins and urethane rubbers. It causes bladder, liver, lung, and other neoplasms.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Aromatic diamine used in the plastics industry as curing agent for epoxy resins and urethane rubbers. It causes bladder, liver, lung, and other neoplasms.

Chemical Identity

Chemical Information

Molecular Formula
C13H12Cl2N2
Molecular Weight
267.15 g/mol
CAS Registry No.
101-14-4
IUPAC Name
4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline
InChIKey
IBOFVQJTBBUKMU-UHFFFAOYSA-N
SMILES
C1=CC(=C(C=C1CC2=CC(=C(C=C2)N)Cl)Cl)N
MeSH Unique ID
D008753
Source
PubChem CID 7543

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • 3,3'-Dichloro-4,4'-Diaminodiphenylmethane
  • 4,4'-Methylenebis(2-chloroaniline)
  • MBOCA
  • Methylene Bis(chloroaniline)

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, analysis, chemical synthesis, chemistry, classification, economics, history, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity.

MeSH Record

History Note

91(77); was see under BENZHYDRYL COMPOUNDS 1977-90

MeSH Record

Previous Indexing

  • Aniline Compounds (1974-1976)
  • Benzhydryl Compounds (1975-1976)
  • Hydrocarbons, Chlorinated (1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Methylenebis(chloroaniline). Medical Subject Headings (MeSH). 2026. Unique ID D008753. http://id.nlm.nih.gov/mesh/2026/D008753
  2. Methylenebis(chloroaniline). In: Wikipedia. https://en.wikipedia.org/wiki/4,4%27-Methylenebis(2-chloroaniline)
  3. Methylenebis(chloroaniline). In: Wikidata. https://www.wikidata.org/wiki/Q2257591
  4. Methylenebis(chloroaniline). In: PubChem Compound. CID 7543. https://pubchem.ncbi.nlm.nih.gov/compound/7543