Structured Summary
Abstract
A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
Chemical Identity
Chemical Information
- Molecular Formula
- C16H16ClN3O3S
- Molecular Weight
- 365.8 g/mol
- CAS Registry No.
- 17560-51-9
- IUPAC Name
- 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide
- InChIKey
- AQCHWTWZEMGIFD-UHFFFAOYSA-N
- SMILES
- CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl
- MeSH Unique ID
- D008788
- Source
- PubChem CID 4170
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- Diulo
- Microx
- Mykrox
- SR-720-22
- Zaroxolyn
- SR 720 22
- SR72022
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(75); was see under DIURETICS, SULFAMYL 1975-90
MeSH Record
Previous Indexing
- Diuretics, Sulfamyl (1974)
- Quinazolines (1971-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Metolazone. Medical Subject Headings (MeSH). 2026. Unique ID D008788. http://id.nlm.nih.gov/mesh/2026/D008788
- Metolazone. In: Wikipedia. https://en.wikipedia.org/wiki/Metolazone
- Metolazone. In: Wikidata. https://www.wikidata.org/wiki/Q1169561
- Metolazone. In: PubChem Compound. CID 4170. https://pubchem.ncbi.nlm.nih.gov/compound/4170