Chemicals and Drugs

Minichromosome Maintenance Proteins

A family of proteins that were originally identified in SACCHAROMYCES CEREVISIAE as being essential for maintaining the structure of minichromosomes00. They form into a protein complex that has helicase activity and is involved in a variety of DNA-related functions including replication elongation, RNA transcription, chromatin remodeling, and genome stability.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of proteins that were originally identified in SACCHAROMYCES CEREVISIAE as being essential for maintaining the structure of minichromosomes00. They form into a protein complex that has helicase activity and is involved in a variety of DNA-related functions including replication elongation, RNA transcription, chromatin remodeling, and genome stability.

MeSH Record

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MeSH Record

Synonyms

7 entry terms
  • Maintenance Proteins, Minichromosome
  • MCM Protein Complex
  • MCM2-7 Complex
  • MCM2-7 Helicase
  • Helicase, MCM2-7
  • MCM2 7 Complex
  • MCM2 7 Helicase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics

MeSH Record

History Note

2014

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.040w.025w.159.186w
  2. D08.811w.399w.340.186w
  3. D12.776w.167.409w
  4. D12.776w.660w.235.500w
  5. D12.776w.664w.235.750w

AMA Style

References

  1. National Library of Medicine. Minichromosome Maintenance Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D064110. http://id.nlm.nih.gov/mesh/2026/D064110
  2. Minichromosome Maintenance Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/Minichromosome_maintenance
  3. Minichromosome Maintenance Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q3858415