Chemicals and Drugs

Minocycline

A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.

Chemical Identity

Chemical Information

Molecular Formula
C23H27N3O7
Molecular Weight
457.5 g/mol
IUPAC Name
(4S,4aS,5aR,12aR)-2-carbamoyl-7-(dimethylamino)-4-(dimethylazaniumyl)-10,11,12a-trihydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracen-1-olate
InChIKey
FFTVPQUHLQBXQZ-KVUCHLLUSA-N
SMILES
C[NH+](C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)[O-])O)O)O)N(C)C
MeSH Unique ID
D008911
Source
PubChem CID 51537604

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

37 entry terms
  • Akamin
  • Akne-Puren
  • Aknemin
  • Aknin-Mino
  • Aknosan
  • Apo-Minocycline
  • Arestin
  • Blemix
  • Cyclomin
  • Cyclops
  • Dentomycin
  • Dynacin
  • Icht-Oral
  • Klinomycin
  • Lederderm
  • Mestacine
  • Minakne
  • Mino-Wolff
  • Minocin
  • Minocin MR
  • Minoclir
  • Minocycline Hydrochloride
  • Minocycline Monohydrochloride
  • Minocycline, (4R-(4 alpha,4a beta,5a beta,12a beta))-Isomer
  • Minolis
  • Minomycin
  • Minoplus
  • Minotab
  • Minox 50
  • Mynocine
  • Akne Puren
  • Aknin Mino
  • Apo Minocycline
  • Hydrochloride, Minocycline
  • Icht Oral
  • Mino Wolff
  • Monohydrochloride, Minocycline

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(73); was see under TETRACYCLINES 1973-90

MeSH Record

Previous Indexing

  • Tetracycline (1966-1972)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.847w.562.900w.550w
  2. D04w.615w.562.900w.550w

AMA Style

References

  1. National Library of Medicine. Minocycline. Medical Subject Headings (MeSH). 2026. Unique ID D008911. http://id.nlm.nih.gov/mesh/2026/D008911
  2. Minocycline. In: Wikipedia. https://en.wikipedia.org/wiki/Minocycline
  3. Minocycline. In: Wikidata. https://www.wikidata.org/wiki/Q415336
  4. Minocycline. In: PubChem Compound. CID 51537604. https://pubchem.ncbi.nlm.nih.gov/compound/51537604