Phenomena and Processes

Minor Histocompatibility Loci

Genetic loci responsible for the encoding of histocompatibility antigens other than those encoded by the MAJOR HISTOCOMPATIBILITY COMPLEX. The antigens encoded by these genes are often responsible for graft rejection in cases where histocompatibility has been established by standard tests. The location of some of these loci on the X and Y chromosomes explains why grafts from males to females may be rejected while grafts from females to males are accepted. In the mouse roughly 30 minor histocompatibility loci have been recognized, comprising more than 500 genes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Genetic loci responsible for the encoding of histocompatibility antigens other than those encoded by the MAJOR HISTOCOMPATIBILITY COMPLEX. The antigens encoded by these genes are often responsible for graft rejection in cases where histocompatibility has been established by standard tests. The location of some of these loci on the X and Y chromosomes explains why grafts from males to females may be rejected while grafts from females to males are accepted. In the mouse roughly 30 minor histocompatibility loci have been recognized, comprising more than 500 genes.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

5 entry terms
  • Histocompatibility Loci, Minor
  • Histocompatibility Locus, Minor
  • Loci, Minor Histocompatibility
  • Locus, Minor Histocompatibility
  • Minor Histocompatibility Locus

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

83

MeSH Record

Previous Indexing

  • H-2 Antigens (1978-1982)
  • Histocompatibility Antigens (1973-1982)
  • T Lymphocytes (1973-1982)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Minor Histocompatibility Loci. Medical Subject Headings (MeSH). 2026. Unique ID D008912. http://id.nlm.nih.gov/mesh/2026/D008912
  2. Minor Histocompatibility Loci. In: Wikidata. https://www.wikidata.org/wiki/Q70710874