Mitoxantrone

Structured Summary

Abstract

An anthracenedione-derived antineoplastic agent.

Chemical Identity

Chemical Information

Molecular Formula: C₂₂H₂₈N₄O₆
Molecular Weight: 444.5 g/mol
CAS Registry No.: 65271-80-9
IUPAC Name: 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione
InChIKey: KKZJGLLVHKMTCM-UHFFFAOYSA-N
SMILES: C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO
MeSH Unique ID: D008942
Source: PubChem CID 4212

MeSH Record

Classification

Broader headings

Anthraquinones

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

30 entry terms

DHAQ
Mitozantrone
CL-232325
Mitoxantrone Acetate
Mitoxantrone Hydrochloride
Mitroxone
NSC-279836
NSC-287836
NSC-299195
NSC-301739
NSC-301739D
Novantron
Novantrone
Onkotrone
Pralifan
Ralenova
Acetate, Mitoxantrone
CL 232325
CL232325
Hydrochloride, Mitoxantrone
NSC 279836
NSC 287836
NSC 299195
NSC 301739
NSC 301739D
NSC279836
NSC287836
NSC299195
NSC301739
NSC301739D

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

MeSH Record

Previous Indexing

Anthraquinones (1966-1986)

MeSH Hierarchy

Tree Numbers

D02 w.455 w.426 w.559 w.847 w.117.380.625 w.500w
D02 w.806 w.100 w.500w
D04 w.615 w.125.380.625 w.500w

MeSH Record

NLM Classification

QV 269

AMA Style

References

National Library of Medicine. Mitoxantrone. Medical Subject Headings (MeSH). 2026. Unique ID D008942. http://id.nlm.nih.gov/mesh/2026/D008942
Mitoxantrone. In: Wikipedia. https://en.wikipedia.org/wiki/Mitoxantrone
Mitoxantrone. In: Wikidata. https://www.wikidata.org/wiki/Q239426
Mitoxantrone. In: PubChem Compound. CID 4212. https://pubchem.ncbi.nlm.nih.gov/compound/4212