Structured Summary
Abstract
Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.
MeSH Record
Classification
Broader headings
Narrower headings
- 2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine
- 4-Hydroxybenzoate-3-Monooxygenase
- Benzoate 4-Monooxygenase
- Catechol Oxidase
- Cytochrome P-450 Enzyme System
- Dopamine beta-Hydroxylase
- Fatty Acid Desaturases
- gamma-Butyrobetaine Dioxygenase
- Heme Oxygenase (Decyclizing)
- Kynurenine 3-Monooxygenase
- Phenylalanine Hydroxylase
- Prolyl Hydroxylases
- Prostaglandin-Endoperoxide Synthases
- Squalene Monooxygenase
- Trans-Cinnamate 4-Monooxygenase
- Tryptophan Hydroxylase
- Tyrosine 3-Monooxygenase
- Vitamin K Epoxide Reductases
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
13 entry terms
- Hydroxylase
- Hydroxylases
- Mixed Function Oxidase
- Mixed Function Oxidases
- Mixed Function Oxygenase
- Monooxygenase
- Monooxygenases
- Function Oxidase, Mixed
- Function Oxygenase, Mixed
- Oxidase, Mixed Function
- Oxidases, Mixed Function
- Oxygenase, Mixed Function
- Oxygenases, Mixed Function
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
do not confuse with HYDRO-LYASES
MeSH Record
History Note
2003 (1966)
MeSH Hierarchy
Tree Number
MeSH Record
NLM Classification
QU 140
AMA Style
References
- National Library of Medicine. Mixed Function Oxygenases. Medical Subject Headings (MeSH). 2026. Unique ID D006899. http://id.nlm.nih.gov/mesh/2026/D006899
- Mixed Function Oxygenases. In: Wikidata. https://www.wikidata.org/wiki/Q67493890