Diseases

Mobius Syndrome

A syndrome of congenital facial paralysis, frequently associated with abducens palsy and other congenital abnormalities including lingual palsy, clubfeet, brachial disorders, cognitive deficits, and pectoral muscle defects. Pathologic findings are variable and include brain stem nuclear aplasia, facial nerve aplasia, and facial muscle aplasia, consistent with a multifactorial etiology. (Adams et al., Principles of Neurology, 6th ed, p1020)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A syndrome of congenital facial paralysis, frequently associated with abducens palsy and other congenital abnormalities including lingual palsy, clubfeet, brachial disorders, cognitive deficits, and pectoral muscle defects. Pathologic findings are variable and include brain stem nuclear aplasia, facial nerve aplasia, and facial muscle aplasia, consistent with a multifactorial etiology. (Adams et al., Principles of Neurology, 6th ed, p1020)

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

9 entry terms
  • Congenital Oculofacial Paralysis, Moebius
  • Congenital Ophthalmoplegia and Facial Paresis
  • Moebius Congenital Oculofacial Paralysis
  • Moebius Sequence
  • Moebius Spectrum
  • Moebius Syndrome
  • Möbius Sequence
  • Mobius Syndromes
  • Moebius Syndromes

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2000; use FACIAL PARALYSIS 1997-1999

MeSH Record

Previous Indexing

  • Facial Paralysis (1966-1999)

MeSH Hierarchy

Tree Numbers

  1. C07.465w.299.825w
  2. C10w.292w.319.825w
  3. C10w.292w.562.700w.375.750w
  4. C11w.590.436w.400.750w
  5. C16w.131w.077w.578w
  6. C16w.614.595w

AMA Style

References

  1. National Library of Medicine. Mobius Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D020331. http://id.nlm.nih.gov/mesh/2026/D020331
  2. Mobius Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Moebius_syndrome
  3. Mobius Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q1418152