Chemicals and Drugs

Mucin-1

Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

24 entry terms
  • Antigen CA-15-3
  • Antigens, CD227
  • CA 15-3 Antigen
  • CA 15.3 Antigen
  • CA-15-3 Antigen
  • CD227 Antigen
  • Episialin
  • Epithelial Membrane Antigen
  • Epithelial Mucin, Polymorphic
  • Muc1 Mucin
  • Polymorphic Epithelial Mucin
  • Antigen CA 15 3
  • Antigen, CA 15-3
  • Antigen, CA 15.3
  • Antigen, CA-15-3
  • Antigen, CD227
  • Antigen, Epithelial Membrane
  • CA 15 3 Antigen
  • CA-15-3, Antigen
  • CD227 Antigens
  • Membrane Antigen, Epithelial
  • Mucin 1
  • Mucin, Muc1
  • Mucin, Polymorphic Epithelial

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2009(1995)

MeSH Record

Previous Indexing

  • Antigens, Neoplasm (1986-1988)
  • Antigens, Tumor-Associated, Carbohydrate (1989-1994)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.560w
  2. D09w.400w.430w.900w.631w.115w
  3. D12.776w.395w.550w.560w
  4. D12.776w.395w.560w.631w.115w
  5. D12.776w.543w.550w.530w
  6. D23.050w.285.050.300w
  7. D23.050w.550w.325.300w
  8. D23.101w.140.075.300w

AMA Style

References

  1. National Library of Medicine. Mucin-1. Medical Subject Headings (MeSH). 2026. Unique ID D018396. http://id.nlm.nih.gov/mesh/2026/D018396
  2. Mucin-1. In: Wikipedia. https://en.wikipedia.org/wiki/Mucin_short_variant_S1
  3. Mucin-1. In: Wikidata. https://www.wikidata.org/wiki/Q21145188