Diseases

Multiple Sclerosis

An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

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MeSH Record

Synonyms

5 entry terms
  • MS (Multiple Sclerosis)
  • Sclerosis, Disseminated
  • Disseminated Sclerosis
  • Sclerosis, Multiple
  • Multiple Sclerosis, Acute Fulminating

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Hierarchy

Tree Numbers

  1. C10w.114.375w.500w
  2. C10w.314w.350w.500w
  3. C20w.111w.258.250w.500w

MeSH Record

NLM Classification

WL 360

AMA Style

References

  1. National Library of Medicine. Multiple Sclerosis. Medical Subject Headings (MeSH). 2026. Unique ID D009103. http://id.nlm.nih.gov/mesh/2026/D009103
  2. Multiple Sclerosis. In: Wikipedia. https://en.wikipedia.org/wiki/Multiple_sclerosis
  3. Multiple Sclerosis. In: Wikidata. https://www.wikidata.org/wiki/Q8277