Chemicals and Drugs

Muscarinic Antagonists

Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

15 entry terms
  • Antimuscarinic
  • Antimuscarinic Agent
  • Antimuscarinic Agents
  • Antimuscarinics
  • Cholinergic Muscarinic Antagonist
  • Cholinergic Muscarinic Antagonists
  • Muscarinic Antagonist
  • Agent, Antimuscarinic
  • Agents, Antimuscarinic
  • Antagonist, Cholinergic Muscarinic
  • Antagonist, Muscarinic
  • Antagonists, Cholinergic Muscarinic
  • Antagonists, Muscarinic
  • Muscarinic Antagonist, Cholinergic
  • Muscarinic Antagonists, Cholinergic

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

95; ANTIMUSCARINIC AGENTS was see PARASYMPATHOLYTICS 1969-94

MeSH Record

Previous Indexing

  • Parasympatholytics (1966-1994)

MeSH Hierarchy

Tree Numbers

  1. D27.505.519w.625.120.200w.500w
  2. D27.505.696.577.120.200w.500w

MeSH Record

NLM Classification

QV 132

AMA Style

References

  1. National Library of Medicine. Muscarinic Antagonists. Medical Subject Headings (MeSH). 2026. Unique ID D018727. http://id.nlm.nih.gov/mesh/2026/D018727
  2. Muscarinic Antagonists. In: Wikipedia. https://en.wikipedia.org/wiki/Muscarinic_antagonist
  3. Muscarinic Antagonists. In: Wikidata. https://www.wikidata.org/wiki/Q3001265