Chemicals and Drugs

Muscimol

A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

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See Also

MeSH Record

Synonyms

2 entry terms
  • Agarin
  • Pantherine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

86(79); was see under OXAZOLES 1979-85

MeSH Record

Previous Indexing

  • Mycotoxins (1967-1978)
  • Oxazoles (1966-1978)
  • Toxins (1966)

MeSH Hierarchy

Tree Numbers

  1. D03w.383.129w.462.470w
  2. D23.946w.587w.587w

AMA Style

References

  1. National Library of Medicine. Muscimol. Medical Subject Headings (MeSH). 2026. Unique ID D009118. http://id.nlm.nih.gov/mesh/2026/D009118
  2. Muscimol. In: Wikipedia. https://en.wikipedia.org/wiki/Muscimol
  3. Muscimol. In: Wikidata. https://www.wikidata.org/wiki/Q412504