Structured Summary
Abstract
DNA repair proteins that include the bacterial MutS DNA mismatch-binding protein and its eukaryotic homologs that function in DNA MISMATCH REPAIR and recombination of DNA during MEIOSIS. MutS has a conserved mismatch recognition domain characterized by GxFxE, or similar AMINO ACID MOTIFS that also occur in eukaryotic homologs such as MSH1, MSH6, and MSH8. All MutS proteins also contain a highly-conserved ATP-binding domain and most have weak ATPase activity.
MeSH Record
Classification
Related Concepts
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MeSH Record
Synonyms
11 entry terms
- MutS Protein
- Protein, MutS
- MutS Homolog
- MutS Homolog Protein
- MutS Homolog Proteins
- MutS Homologs
- Homolog Protein, MutS
- Homolog Proteins, MutS
- Homolog, MutS
- Protein, MutS Homolog
- Proteins, MutS Homolog
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2018
MeSH Record
Previous Indexing
- Adenosine Triphosphatases (1997-2017)
- DNA-Binding Proteins (1997-2017)
- MutS DNA Mismatch-Binding Protein (2006-2017)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. MutS Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D000074080. http://id.nlm.nih.gov/mesh/2026/D000074080
- MutS Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q113191773