Structured Summary
Abstract
A pyrazole diuretic with long duration and high capacity of action. It was proposed for kidney failure and hypertension but was withdrawn worldwide because of severe neurological effects.
Chemical Identity
Chemical Information
- Molecular Formula
- C11H11Cl2N3O
- Molecular Weight
- 272.13 g/mol
- CAS Registry No.
- 55294-15-0
- IUPAC Name
- 5-amino-2-[1-(3,4-dichlorophenyl)ethyl]-4H-pyrazol-3-one
- InChIKey
- RLWRMIYXDPXIEX-UHFFFAOYSA-N
- SMILES
- CC(C1=CC(=C(C=C1)Cl)Cl)N2C(=O)CC(=N2)N
- MeSH Unique ID
- D009156
- Source
- PubChem CID 41386
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
2 entry terms
- Bay G 2821
- G 2821, Bay
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(80); was see under PYRAZOLES 1980-90
MeSH Record
Previous Indexing
- Pyrazoles (1966-1979)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Muzolimine. Medical Subject Headings (MeSH). 2026. Unique ID D009156. http://id.nlm.nih.gov/mesh/2026/D009156
- Muzolimine. In: Wikipedia. https://en.wikipedia.org/wiki/Muzolimine
- Muzolimine. In: Wikidata. https://www.wikidata.org/wiki/Q3868794
- Muzolimine. In: PubChem Compound. CID 41386. https://pubchem.ncbi.nlm.nih.gov/compound/41386