Chemicals and Drugs

Myeloid Differentiation Factor 88

An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • MyD88 Protein
  • TLR Signal Adaptor Protein MyD88
  • Toll-Like Receptor Signal Adaptor Protein MyD88
  • Toll Like Receptor Signal Adaptor Protein MyD88

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1990)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.360.024w.311
  2. D12.776w.157w.057w.074
  3. D12.776w.476.024w.390

AMA Style

References

  1. National Library of Medicine. Myeloid Differentiation Factor 88. Medical Subject Headings (MeSH). 2026. Unique ID D053594. http://id.nlm.nih.gov/mesh/2026/D053594
  2. Myeloid Differentiation Factor 88. In: Wikidata. https://www.wikidata.org/wiki/Q76938089