Chemicals and Drugs

Myosin Subfragments

Parts of the myosin molecule resulting from cleavage by proteolytic enzymes (PAPAIN; TRYPSIN; or CHYMOTRYPSIN) at well-localized regions. Study of these isolated fragments helps to delineate the functional roles of different parts of myosin. Two of the most common subfragments are myosin S-1 and myosin S-2. S-1 contains the heads of the heavy chains plus the light chains and S-2 contains part of the double-stranded, alpha-helical, heavy chain tail (myosin rod).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Parts of the myosin molecule resulting from cleavage by proteolytic enzymes (PAPAIN; TRYPSIN; or CHYMOTRYPSIN) at well-localized regions. Study of these isolated fragments helps to delineate the functional roles of different parts of myosin. Two of the most common subfragments are myosin S-1 and myosin S-2. S-1 contains the heads of the heavy chains plus the light chains and S-2 contains part of the double-stranded, alpha-helical, heavy chain tail (myosin rod).

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

37 entry terms
  • Subfragments, Myosin
  • ATPase, Actin-S1
  • Actin S1 ATPase
  • Actoheavy Meromyosin
  • Actomyosin Subfragment 1 ATPase
  • Actomyosin Subfragments
  • H-Meromyosin
  • Heavy Meromyosin
  • Heavy Meromyosin Subfragment-1
  • Heavy Meromyosin Subfragment-2
  • Light Meromyosin
  • Meromyosin Subfragments
  • Myosin Rod
  • Myosin S-1
  • Myosin S-2
  • Myosin Subfragment-1
  • Myosin Subfragment-2
  • ATPase, Actin S1
  • Actin-S1 ATPase
  • H Meromyosin
  • Heavy Meromyosin Subfragment 1
  • Heavy Meromyosin Subfragment 2
  • Meromyosin Subfragment-1, Heavy
  • Meromyosin Subfragment-2, Heavy
  • Meromyosin, Actoheavy
  • Meromyosin, Heavy
  • Meromyosin, Light
  • Myosin S 1
  • Myosin S 2
  • Myosin Subfragment 1
  • Myosin Subfragment 2
  • Subfragment-1, Heavy Meromyosin
  • Subfragment-1, Myosin
  • Subfragment-2, Heavy Meromyosin
  • Subfragment-2, Myosin
  • Subfragments, Actomyosin
  • Subfragments, Meromyosin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

90; MEROMYOSINS was heading 1971-90 (Prov 1971-73)

MeSH Record

Previous Indexing

  • Muscle Proteins (1966-1970)
  • Myosin (1966-1989)
  • Peptide Fragments (1974-1989)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Myosin Subfragments. Medical Subject Headings (MeSH). 2026. Unique ID D015879. http://id.nlm.nih.gov/mesh/2026/D015879
  2. Myosin Subfragments. In: Wikidata. https://www.wikidata.org/wiki/Q76855003