Structured Summary
Abstract
Serine/threonine protein kinase responsible for various SKELETAL MUSCLE functions; HEART CONDUCTION SYSTEM activity; calcium HOMEOSTASIS; calcium uptake by SARCOPLASMIC RETICULUM and SYNAPTIC PLASTICITY. It is encoded by the DMPK gene and its abnormal EXPANDED TRINUCLEOTIDE REPEAT of CTG in the 3'-UTR is associated with MYOTONIC DYSTROPHY 1.
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Synonyms
16 entry terms
- DM Protein Kinase
- DM-Kinase
- DM1PK Protein
- DMPK Protein
- MDGP Protein
- MDPK Protein
- Myotonic Dystrophy Protein Kinase
- DM Kinase
- Kinase, DM Protein
- Kinase, Myotonin-Protein
- Myotonin Protein Kinase
- Protein Kinase, DM
- Protein, DM1PK
- Protein, DMPK
- Protein, MDGP
- Protein, MDPK
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Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2015
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AMA Style
References
- National Library of Medicine. Myotonin-Protein Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D065636. http://id.nlm.nih.gov/mesh/2026/D065636
- Myotonin-Protein Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q21143665