Chemicals and Drugs

NADPH Oxidase 1

An NADPH oxidase that functions as a voltage-gated proton channel expressed by PHAGOCYTES, especially in the colon. It regulates intracellular pH, generates SUPEROXIDES upon activation by PHAGOCYTOSIS, and may play a role in INNATE IMMUNITY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An NADPH oxidase that functions as a voltage-gated proton channel expressed by PHAGOCYTES, especially in the colon. It regulates intracellular pH, generates SUPEROXIDES upon activation by PHAGOCYTOSIS, and may play a role in INNATE IMMUNITY.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • Mitogenic Oxidase 1
  • NOX1 Protein
  • Oxidase 1, Mitogenic
  • Oxidase 1, NADPH

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018 (1999)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.682w.608.575.750
  2. D12.776w.331w.894.750
  3. D12.776w.543w.653.750

AMA Style

References

  1. National Library of Medicine. NADPH Oxidase 1. Medical Subject Headings (MeSH). 2026. Unique ID D000074624. http://id.nlm.nih.gov/mesh/2026/D000074624
  2. NADPH Oxidase 1. In: Wikidata. https://www.wikidata.org/wiki/Q24774475