Chemicals and Drugs

NADPH Oxidase 5

An NADPH oxidase that contains four EF HANDS and is expressed primarily by SPERMATOCYTES and LYMPHOCYTES, as well as by endothelial cells. It functions as a calcium-dependent proton channel to generate SUPEROXIDES that regulate cell growth, APOPTOSIS; and PHYSIOLOGIC ANGIOGENESIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An NADPH oxidase that contains four EF HANDS and is expressed primarily by SPERMATOCYTES and LYMPHOCYTES, as well as by endothelial cells. It functions as a calcium-dependent proton channel to generate SUPEROXIDES that regulate cell growth, APOPTOSIS; and PHYSIOLOGIC ANGIOGENESIS.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

1 entry terms
  • Nox5 Protein

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Membrane Proteins (2001-2017)
  • NADPH Oxidases (2001-2017)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.682w.608.575.968
  2. D12.776w.331w.894.968
  3. D12.776w.543w.653.968

AMA Style

References

  1. National Library of Medicine. NADPH Oxidase 5. Medical Subject Headings (MeSH). 2026. Unique ID D000074664. http://id.nlm.nih.gov/mesh/2026/D000074664
  2. NADPH Oxidase 5. In: Wikidata. https://www.wikidata.org/wiki/Q107662974