Chemicals and Drugs

Nafronyl

A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.

Chemical Identity

Chemical Information

Molecular Formula
C24H33NO3
Molecular Weight
383.5 g/mol
CAS Registry No.
31329-57-4
IUPAC Name
2-(diethylamino)ethyl 2-(naphthalen-1-ylmethyl)-3-(oxolan-2-yl)propanoate
InChIKey
KBAFPSLPKGSANY-UHFFFAOYSA-N
SMILES
CCN(CC)CCOC(=O)C(CC1CCCO1)CC2=CC=CC3=CC=CC=C32
MeSH Unique ID
D009257
Source
PubChem CID 4417

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

25 entry terms
  • Naftidrofuryl
  • Artocoron
  • Azunaftil
  • Di-Actane
  • Dusodril
  • Gévatran
  • LS-121
  • Nafronyl Oxalate
  • Nafronyloxalate
  • Nafti Von Ct
  • Nafti-Puren
  • Nafti-Ratiopharm
  • Naftifurin Oxalate
  • Naftilong
  • Naftilux
  • Praxilene
  • Praxilène
  • Di Actane
  • LS 121
  • LS121
  • Nafti Puren
  • Nafti Ratiopharm
  • NaftiRatiopharm
  • Oxalate, Nafronyl
  • Oxalate, Naftifurin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under FURANS 1975-90

MeSH Record

Previous Indexing

  • Diethylamines (1974)
  • Furans (1971-1974)
  • Naphthalenes (1971-1974)
  • Propionates (1971-1974)

MeSH Hierarchy

Tree Number

  1. D03w.383.312.620w

AMA Style

References

  1. National Library of Medicine. Nafronyl. Medical Subject Headings (MeSH). 2026. Unique ID D009257. http://id.nlm.nih.gov/mesh/2026/D009257
  2. Nafronyl. In: Wikipedia. https://en.wikipedia.org/wiki/Naftidrofuryl
  3. Nafronyl. In: Wikidata. https://www.wikidata.org/wiki/Q425867
  4. Nafronyl. In: PubChem Compound. CID 4417. https://pubchem.ncbi.nlm.nih.gov/compound/4417