Chemicals and Drugs

Naproxen

An anti-inflammatory agent with analgesic and antipyretic properties. Both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An anti-inflammatory agent with analgesic and antipyretic properties. Both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout.

Chemical Identity

Chemical Information

Molecular Formula
C14H14O3
Molecular Weight
230.26 g/mol
CAS Registry No.
22204-53-1
IUPAC Name
(2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
InChIKey
CMWTZPSULFXXJA-VIFPVBQESA-N
SMILES
C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O
MeSH Unique ID
D009288
Source
PubChem CID 156391

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Methoxypropiocin
  • Aleve
  • Anaprox
  • Naprosin
  • Naprosyn
  • Naproxen Sodium
  • Proxen
  • Sodium Naproxenate
  • Synflex
  • Naproxenate, Sodium
  • Sodium, Naproxen

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

78(75); was see under NAPHTHALENEACETIC ACIDS 1975-77

MeSH Record

Previous Indexing

  • Methyl Ethers (1973-1974)
  • Naphthalenes (1972-1974)
  • Propionates (1972-1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.847w.638.472.500w
  2. D04w.615w.638.472.450w

MeSH Record

NLM Classification

QV 95

AMA Style

References

  1. National Library of Medicine. Naproxen. Medical Subject Headings (MeSH). 2026. Unique ID D009288. http://id.nlm.nih.gov/mesh/2026/D009288
  2. Naproxen. In: Wikipedia. https://en.wikipedia.org/wiki/Naproxen
  3. Naproxen. In: Wikidata. https://www.wikidata.org/wiki/Q1215575
  4. Naproxen. In: PubChem Compound. CID 156391. https://pubchem.ncbi.nlm.nih.gov/compound/156391