Chemicals and Drugs

Nateglinide

A phenylalanine and cyclohexane derivative that acts as a hypoglycemic agent by stimulating the release of insulin from the pancreas. It is used in the treatment of TYPE 2 DIABETES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A phenylalanine and cyclohexane derivative that acts as a hypoglycemic agent by stimulating the release of insulin from the pancreas. It is used in the treatment of TYPE 2 DIABETES.

Chemical Identity

Chemical Information

Molecular Formula
C19H27NO3
Molecular Weight
317.4 g/mol
CAS Registry No.
105816-05-5
IUPAC Name
(2S)-3-phenyl-2-[(4-propan-2-ylcyclohexanecarbonyl)amino]propanoic acid
InChIKey
OELFLUMRDSZNSF-JCYILVPMSA-N
SMILES
CC(C)C1CCC(CC1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O
MeSH Unique ID
D000077715
Source
PubChem CID 60026

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • Nate-Glinide
  • Senaglinide
  • A 4166
  • A-4166
  • AY 4166
  • AY-4166
  • DJN 608
  • Fastic
  • N-((4-Isopropylcyclohexyl)carbonyl)phenylalanine
  • Nateglinide, (D-Phe)-isomer
  • Nateglinide, (cis,D-Phe)-isomer
  • Starlix
  • Starsis
  • A4166
  • AY4166

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1989)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Nateglinide. Medical Subject Headings (MeSH). 2026. Unique ID D000077715. http://id.nlm.nih.gov/mesh/2026/D000077715
  2. Nateglinide. In: Wikipedia. https://en.wikipedia.org/wiki/Nateglinide
  3. Nateglinide. In: Wikidata. https://www.wikidata.org/wiki/Q2254797
  4. Nateglinide. In: PubChem Compound. CID 60026. https://pubchem.ncbi.nlm.nih.gov/compound/60026