Structured Summary
Abstract
A cation transport protein that shares structural homology with prokaryotic and eukaryotic transport proteins. In mammals, it is a MACROPHAGE-specific antiporter, transporting metal ions in either direction against a proton gradient, and localizes to membranes of late ENDOSOMES and LYSOSOMES, where it may contribute to antimicrobial activity.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
6 entry terms
- Natural Resistance-associated Macrophage Protein
- Nramp Protein
- Nramp1 Protein
- SLC11A1 Protein
- Solute Carrier 11a1
- Solute Carrier Family 11-(proton-coupled divalent metal ion transporters), Member 1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2026 (1993)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Natural Resistance-associated Macrophage Protein 1. Medical Subject Headings (MeSH). 2026. Unique ID D000099173. http://id.nlm.nih.gov/mesh/2026/D000099173
- Natural Resistance-associated Macrophage Protein 1. In: Wikidata. https://www.wikidata.org/wiki/Q21124081