Chemicals and Drugs

Nedocromil

A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including EOSINOPHILS; NEUTROPHILS; MACROPHAGES; MAST CELLS; MONOCYTES; AND PLATELETS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including EOSINOPHILS; NEUTROPHILS; MACROPHAGES; MAST CELLS; MONOCYTES; AND PLATELETS.

Chemical Identity

Chemical Information

Molecular Formula
C19H17NO7
Molecular Weight
371.3 g/mol
CAS Registry No.
69049-73-6
IUPAC Name
9-ethyl-4,6-dioxo-10-propylpyrano[3,2-g]quinoline-2,8-dicarboxylic acid
InChIKey
RQTOOFIXOKYGAN-UHFFFAOYSA-N
SMILES
CCCC1=C2C(=CC3=C1OC(=CC3=O)C(=O)O)C(=O)C=C(N2CC)C(=O)O
MeSH Unique ID
D017835
Source
PubChem CID 50294

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

21 entry terms
  • 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid
  • Alocril
  • Brionil
  • Cetimil
  • FPL-59002
  • Halamid
  • Irtan
  • Nedocromil Calcium
  • Nedocromil Sodium
  • Nedocromil, Calcium Salt (1:1)
  • Nedocromil, Disodium Salt
  • Nedocromil, Disodium salt, Hydrate
  • Rapitil
  • Tilad
  • Tilade
  • Tilaire
  • Tilavist
  • Calcium, Nedocromil
  • FPL 59002
  • FPL59002
  • Sodium, Nedocromil

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

94; was NEDOCROMIL (NM) 1984-93

MeSH Record

Previous Indexing

  • Quinolines (1984-1988)
  • Quinolones (1989-1993)

MeSH Hierarchy

Tree Number

  1. D03w.633.100.810.835.830w.550w

AMA Style

References

  1. National Library of Medicine. Nedocromil. Medical Subject Headings (MeSH). 2026. Unique ID D017835. http://id.nlm.nih.gov/mesh/2026/D017835
  2. Nedocromil. In: Wikipedia. https://en.wikipedia.org/wiki/Nedocromil
  3. Nedocromil. In: Wikidata. https://www.wikidata.org/wiki/Q416706
  4. Nedocromil. In: PubChem Compound. CID 50294. https://pubchem.ncbi.nlm.nih.gov/compound/50294