Diseases

Neonatal Myasthenia Gravis

A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)

MeSH Record

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MeSH Record

Synonyms

11 entry terms
  • Myasthenia Gravis, Neonatal
  • Antenatal Myasthenia Gravis
  • Myasthenia Gravis, Neonatal, Persistent
  • Myasthenia Gravis, Neonatal, Transient
  • Myasthenia Gravis, Persistent, Neonatal
  • Myasthenia Gravis, Transient, Neonatal
  • Neonatal Myasthenia Gravis, Persistent
  • Neonatal Myasthenia Gravis, Transient
  • Persistent Neonatal Myasthenia Gravis
  • Transient Neonatal Myasthenia Gravis
  • Myasthenia Gravis, Antenatal

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2000

MeSH Record

Previous Indexing

  • Myasthenia Gravis (1965-1999)

MeSH Hierarchy

Tree Numbers

  1. C10w.114.656w.650
  2. C10w.668w.758w.725w.650
  3. C20w.111w.258.500w.650

AMA Style

References

  1. National Library of Medicine. Neonatal Myasthenia Gravis. Medical Subject Headings (MeSH). 2026. Unique ID D020941. http://id.nlm.nih.gov/mesh/2026/D020941
  2. Neonatal Myasthenia Gravis. In: Wikidata. https://www.wikidata.org/wiki/Q18554667