Diseases

Nephrogenic Diabetes Insipidus

A genetic or acquired polyuric disorder characterized by persistent hypotonic urine and HYPOKALEMIA. This condition is due to renal tubular insensitivity to VASOPRESSIN and failure to reduce urine volume. It may be the result of mutations of genes encoding VASOPRESSIN RECEPTORS or AQUAPORIN-2; KIDNEY DISEASES; adverse drug effects; or complications from PREGNANCY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A genetic or acquired polyuric disorder characterized by persistent hypotonic urine and HYPOKALEMIA. This condition is due to renal tubular insensitivity to VASOPRESSIN and failure to reduce urine volume. It may be the result of mutations of genes encoding VASOPRESSIN RECEPTORS or AQUAPORIN-2; KIDNEY DISEASES; adverse drug effects; or complications from PREGNANCY.

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Classification

Broader headings

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See Also

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Synonyms

13 entry terms
  • Diabetes Insipidus, Nephrogenic
  • ADH-Resistant Diabetes Insipidus
  • Acquired Nephrogenic Diabetes Insipidus
  • Congenital Nephrogenic Diabetes Insipidus
  • Diabetes Insipidus Renalis
  • Diabetes Insipidus, Nephrogenic, Autosomal
  • Diabetes Insipidus, Nephrogenic, Type 1
  • Diabetes Insipidus, Nephrogenic, Type I
  • Diabetes Insipidus, Nephrogenic, Type II
  • Diabetes Insipidus, Nephrogenic, X-Linked
  • Nephrogenic Diabetes Insipidus, Type I
  • Nephrogenic Diabetes Insipidus, Type II
  • Vasopressin-Resistant Diabetes Insipidus

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

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Indexing Annotation

do not confuse with DIABETIC NEPHROPATHIES which refers to diabetes mellitus or with DIABETES INSIPIDUS, NEUROGENIC

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History Note

95

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Previous Indexing

  • Diabetes Insipidus (1966-1994)

MeSH Hierarchy

Tree Numbers

  1. C12.050.351.968w.419w.135w.500w
  2. C12.200.777w.419w.135w.500w
  3. C12.950w.419w.135w.500w

AMA Style

References

  1. National Library of Medicine. Nephrogenic Diabetes Insipidus. Medical Subject Headings (MeSH). 2026. Unique ID D018500. http://id.nlm.nih.gov/mesh/2026/D018500
  2. Nephrogenic Diabetes Insipidus. In: Wikipedia. https://en.wikipedia.org/wiki/Nephrogenic_diabetes_insipidus
  3. Nephrogenic Diabetes Insipidus. In: Wikidata. https://www.wikidata.org/wiki/Q2892779