Structured Summary
Abstract
A basic polypeptide isolated from Streptomyces netropsis. It is cytotoxic and its strong, specific binding to A-T areas of DNA is useful to genetics research.
Chemical Identity
Chemical Information
- Molecular Formula
- C18H26N10O3
- Molecular Weight
- 430.5 g/mol
- CAS Registry No.
- 1438-30-8
- IUPAC Name
- N-[5-[(3-amino-3-iminopropyl)carbamoyl]-1-methylpyrrol-3-yl]-4-[[2-(diaminomethylideneamino)acetyl]amino]-1-methylpyrrole-2-carboxamide
- InChIKey
- IDBIFFKSXLYUOT-UHFFFAOYSA-N
- SMILES
- CN1C=C(C=C1C(=O)NC2=CN(C(=C2)C(=O)NCCC(=N)N)C)NC(=O)CN=C(N)N
- MeSH Unique ID
- D009429
- Source
- PubChem CID 4461
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
6 entry terms
- Congocidine
- Sinanomycin
- IA-887
- Netropsin Hydrochloride
- T-1384
- Hydrochloride, Netropsin
MeSH Record
Aspects Covered
26 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(77); was see under GUANIDINES 1977-90; CONGOCIDINE was (NM) 1973-93
MeSH Record
Previous Indexing
- Guanidines (1966-1976)
- Pyrroles (1966-1976)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Netropsin. Medical Subject Headings (MeSH). 2026. Unique ID D009429. http://id.nlm.nih.gov/mesh/2026/D009429
- Netropsin. In: Wikipedia. https://en.wikipedia.org/wiki/Netropsin
- Netropsin. In: Wikidata. https://www.wikidata.org/wiki/Q3874969
- Netropsin. In: PubChem Compound. CID 4461. https://pubchem.ncbi.nlm.nih.gov/compound/4461