Chemicals and Drugs

Neurosteroids

Endogenous compounds or drugs that affect neuronal excitability through modulation of specific ionotropic receptors (e.g., GABA-A RECEPTORS). Endogenous neurosteroids are steroid hormones de novo synthesized by neurons and glial cells from steroid metabolite precursors (e.g., PREGNENOLONE).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Endogenous compounds or drugs that affect neuronal excitability through modulation of specific ionotropic receptors (e.g., GABA-A RECEPTORS). Endogenous neurosteroids are steroid hormones de novo synthesized by neurons and glial cells from steroid metabolite precursors (e.g., PREGNENOLONE).

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

8 entry terms
  • Neuro-Steroid
  • Neuro-Steroids
  • Neuroactive Steroid
  • Neuroactive Steroids
  • Neurosteroid
  • Neuro Steroid
  • Neuro Steroids
  • Steroid, Neuroactive

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2020(2010)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.625w
  2. D27.505.519w.625.544w
  3. D27.505.696.577.544w

AMA Style

References

  1. National Library of Medicine. Neurosteroids. Medical Subject Headings (MeSH). 2026. Unique ID D000081227. http://id.nlm.nih.gov/mesh/2026/D000081227
  2. Neurosteroids. In: Wikipedia. https://en.wikipedia.org/wiki/Neurosteroid
  3. Neurosteroids. In: Wikidata. https://www.wikidata.org/wiki/Q2659374