Structured Summary
Abstract
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H14N2
- Molecular Weight
- 162.23 g/mol
- CAS Registry No.
- 54-11-5
- IUPAC Name
- 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
- InChIKey
- SNICXCGAKADSCV-JTQLQIEISA-N
- SMILES
- CN1CCC[C@H]1C2=CN=CC=C2
- MeSH Unique ID
- D009538
- Source
- PubChem CID 89594
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
See Also
MeSH Record
Synonyms
2 entry terms
- Nicotine Bitartrate
- Nicotine Tartrate
MeSH Record
Aspects Covered
27 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QV 137
AMA Style
References
- National Library of Medicine. Nicotine. Medical Subject Headings (MeSH). 2026. Unique ID D009538. http://id.nlm.nih.gov/mesh/2026/D009538
- Nicotine. In: Wikipedia. https://en.wikipedia.org/wiki/Nicotine
- Nicotine. In: Wikidata. https://www.wikidata.org/wiki/Q28086552
- Nicotine. In: PubChem Compound. CID 89594. https://pubchem.ncbi.nlm.nih.gov/compound/89594