Chemicals and Drugs

Nifedipine

A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Chemical Identity

Chemical Information

Molecular Formula
C17H18N2O6
Molecular Weight
346.3 g/mol
CAS Registry No.
21829-25-4
IUPAC Name
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey
HYIMSNHJOBLJNT-UHFFFAOYSA-N
SMILES
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
MeSH Unique ID
D009543
Source
PubChem CID 4485

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

20 entry terms
  • Adalat
  • BAY-a-1040
  • Bay-1040
  • Cordipin
  • Cordipine
  • Corinfar
  • Fenigidin
  • Korinfar
  • Nifangin
  • Nifedipine Monohydrochloride
  • Nifedipine-GTIS
  • Procardia
  • Procardia XL
  • Vascard
  • BAY a 1040
  • BAYa1040
  • Bay 1040
  • Bay1040
  • Monohydrochloride, Nifedipine
  • Nifedipine GTIS

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

84(75); was see under PYRIDINES 1975-83

MeSH Record

Previous Indexing

  • Dicarboxylic Acids (1972-1974)
  • Nitrobenzenes (1972-1974)
  • Pyridines (1972-1974)

MeSH Hierarchy

Tree Number

  1. D03w.383.725w.203.540w

MeSH Record

NLM Classification

QV 150

AMA Style

References

  1. National Library of Medicine. Nifedipine. Medical Subject Headings (MeSH). 2026. Unique ID D009543. http://id.nlm.nih.gov/mesh/2026/D009543
  2. Nifedipine. In: Wikipedia. https://en.wikipedia.org/wiki/Nifedipine
  3. Nifedipine. In: Wikidata. https://www.wikidata.org/wiki/Q39111
  4. Nifedipine. In: PubChem Compound. CID 4485. https://pubchem.ncbi.nlm.nih.gov/compound/4485