Structured Summary
Abstract
Acridine antineoplastic agent used in mammary and ovarian tumors. It inhibits RNA synthesis.
Chemical Identity
Chemical Information
- Molecular Formula
- C18H20N4O2
- Molecular Weight
- 324.4 g/mol
- CAS Registry No.
- 4533-39-5
- IUPAC Name
- N',N'-dimethyl-N-(1-nitroacridin-9-yl)propane-1,3-diamine
- InChIKey
- YMVWGSQGCWCDGW-UHFFFAOYSA-N
- SMILES
- CN(C)CCCNC1=C2C(=NC3=CC=CC=C31)C=CC=C2[N+](=O)[O-]
- MeSH Unique ID
- D009564
- Source
- PubChem CID 20628
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- C-283
- Ledakrin
- C 283
- C283
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(85); was see under AMINOACRIDINES 1985-90; was C 283 see under AMINOACRIDINES 1981-84; was C 283 see under ACRIDINES 1975-80
MeSH Record
Previous Indexing
- Acridines (1971-1974)
- Dimethylamines (1973-1974)
- Nitro Compounds (1972-1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Nitracrine. Medical Subject Headings (MeSH). 2026. Unique ID D009564. http://id.nlm.nih.gov/mesh/2026/D009564
- Nitracrine. In: Wikidata. https://www.wikidata.org/wiki/Q27265916
- Nitracrine. In: PubChem Compound. CID 20628. https://pubchem.ncbi.nlm.nih.gov/compound/20628