Chemicals and Drugs

Nocodazole

Nocodazole is an antineoplastic agent which exerts its effect by depolymerizing microtubules.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Nocodazole is an antineoplastic agent which exerts its effect by depolymerizing microtubules.

Chemical Identity

Chemical Information

Molecular Formula
C14H11N3O3S
Molecular Weight
301.32 g/mol
CAS Registry No.
31430-18-9
IUPAC Name
methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
InChIKey
KYRVNWMVYQXFEU-UHFFFAOYSA-N
SMILES
COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
MeSH Unique ID
D015739
Source
PubChem CID 4122

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Oncodazole
  • NSC-238159
  • R-17934
  • R17934
  • NSC 238159
  • NSC238159
  • R 17934

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Antineoplastic Agents (1966-1989)
  • Benzimidazoles (1966-1989)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Nocodazole. Medical Subject Headings (MeSH). 2026. Unique ID D015739. http://id.nlm.nih.gov/mesh/2026/D015739
  2. Nocodazole. In: Wikipedia. https://en.wikipedia.org/wiki/Nocodazole
  3. Nocodazole. In: Wikidata. https://www.wikidata.org/wiki/Q2506092
  4. Nocodazole. In: PubChem Compound. CID 4122. https://pubchem.ncbi.nlm.nih.gov/compound/4122