Structured Summary
Abstract
An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon.
MeSH Record
Classification
Broader headings
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MeSH Record
Synonyms
60 entry terms
- Codon, Nonsense
- Codon, Termination, Premature
- Premature Stop Codon
- Premature Termination Codon
- Codon, Premature Stop
- Codon, Premature Termination
- Codons, Nonsense
- Codons, Premature Stop
- Codons, Premature Termination
- Nonsense Codons
- Premature Stop Codons
- Premature Termination Codons
- Stop Codon, Premature
- Stop Codons, Premature
- Termination Codon, Premature
- Termination Codons, Premature
- Amber Nonsense Codon
- Amber Nonsense Mutation
- Codon, Unassigned
- Mutation, Nonsense
- Nonsense Codon, Amber
- Nonsense Mutation
- Ochre Nonsense Codon
- Ochre Nonsense Mutation
- Opal Nonsense Codon
- Opal Nonsense Mutation
- Unassigned Codon
- Amber Nonsense Codons
- Amber Nonsense Mutations
- Codon, Amber Nonsense
- Codon, Ochre Nonsense
- Codon, Opal Nonsense
- Codons, Amber Nonsense
- Codons, Ochre Nonsense
- Codons, Opal Nonsense
- Codons, Unassigned
- Mutation, Amber Nonsense
- Mutation, Ochre Nonsense
- Mutation, Opal Nonsense
- Mutations, Amber Nonsense
- Mutations, Nonsense
- Mutations, Ochre Nonsense
- Mutations, Opal Nonsense
- Nonsense Codon, Ochre
- Nonsense Codon, Opal
- Nonsense Codons, Amber
- Nonsense Codons, Ochre
- Nonsense Codons, Opal
- Nonsense Mutation, Amber
- Nonsense Mutation, Ochre
- Nonsense Mutation, Opal
- Nonsense Mutations
- Nonsense Mutations, Amber
- Nonsense Mutations, Ochre
- Nonsense Mutations, Opal
- Ochre Nonsense Codons
- Ochre Nonsense Mutations
- Opal Nonsense Codons
- Opal Nonsense Mutations
- Unassigned Codons
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
for amber or ochre suppressor mutations use SUPPRESSION, GENETIC
MeSH Record
History Note
95
MeSH Record
Previous Indexing
- Codon (1975-1994)
- Genetic Code (1966-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Nonsense Codon. Medical Subject Headings (MeSH). 2026. Unique ID D018389. http://id.nlm.nih.gov/mesh/2026/D018389
- Nonsense Codon. In: Wikidata. https://www.wikidata.org/wiki/Q30060492