Phenomena and Processes

Nonsense Mediated mRNA Decay

An mRNA metabolic process that distinguishes a normal STOP CODON from a premature stop codon (NONSENSE CODON) and facilitates rapid degradation of aberrant mRNAs containing premature stop codons.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An mRNA metabolic process that distinguishes a normal STOP CODON from a premature stop codon (NONSENSE CODON) and facilitates rapid degradation of aberrant mRNAs containing premature stop codons.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

3 entry terms
  • Nonsense-Mediated mRNA Decay
  • Decay, Nonsense-Mediated mRNA
  • mRNA Decay, Nonsense-Mediated

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2012

MeSH Record

Previous Indexing

  • Codon, Nonsense (1999-2011)
  • RNA, Messenger/metabolism (1994-2011)

MeSH Hierarchy

Tree Numbers

  1. G02.111.760w.112w
  2. G02.111.780.500w
  3. G03w.839w.112w
  4. G05.308w.700w.112w

AMA Style

References

  1. National Library of Medicine. Nonsense Mediated mRNA Decay. Medical Subject Headings (MeSH). 2026. Unique ID D059365. http://id.nlm.nih.gov/mesh/2026/D059365
  2. Nonsense Mediated mRNA Decay. In: Wikipedia. https://en.wikipedia.org/wiki/Nonsense-mediated_decay
  3. Nonsense Mediated mRNA Decay. In: Wikidata. https://www.wikidata.org/wiki/Q14911527