Chemicals and Drugs

Norethindrone

A synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for CONTRACEPTION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for CONTRACEPTION.

Chemical Identity

Chemical Information

Molecular Formula
C20H26O2
Molecular Weight
298.4 g/mol
CAS Registry No.
68-22-4
IUPAC Name
(8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
InChIKey
VIKNJXKGJWUCNN-XGXHKTLJSA-N
SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34
MeSH Unique ID
D009640
Source
PubChem CID 6230

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • 19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-, (17alpha)-
  • Ethinylnortestosterone
  • Norethisterone
  • Norpregneninolone
  • Conceplan
  • Micronor
  • Monogest
  • Nor-QD
  • Norcolut
  • Norcolute
  • Norethindrone, (1 beta)-Isomer
  • Norlutin
  • Nor QD
  • NorQD

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.668w.651.693.651w

AMA Style

References

  1. National Library of Medicine. Norethindrone. Medical Subject Headings (MeSH). 2026. Unique ID D009640. http://id.nlm.nih.gov/mesh/2026/D009640
  2. Norethindrone. In: Wikipedia. https://en.wikipedia.org/wiki/Norethisterone
  3. Norethindrone. In: Wikidata. https://www.wikidata.org/wiki/Q421352
  4. Norethindrone. In: PubChem Compound. CID 6230. https://pubchem.ncbi.nlm.nih.gov/compound/6230