Chemicals and Drugs

Norethynodrel

A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and ENDOMETRIOSIS. As a contraceptive (CONTRACEPTIVE AGENTS), it has usually been administered in combination with MESTRANOL.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and ENDOMETRIOSIS. As a contraceptive (CONTRACEPTIVE AGENTS), it has usually been administered in combination with MESTRANOL.

Chemical Identity

Chemical Information

Molecular Formula
C20H26O2
Molecular Weight
298.4 g/mol
CAS Registry No.
68-23-5
IUPAC Name
(8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
InChIKey
ICTXHFFSOAJUMG-SLHNCBLASA-N
SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3CCC(=O)C4
MeSH Unique ID
D009641
Source
PubChem CID 6231

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • 19-Norpregn-5(10)-en-20-yn-3-one, 17-hydroxy-, (17alpha)-
  • Norethynodrel, (8 alpha)-(+-)-Isomer

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Norethynodrel. Medical Subject Headings (MeSH). 2026. Unique ID D009641. http://id.nlm.nih.gov/mesh/2026/D009641
  2. Norethynodrel. In: Wikipedia. https://en.wikipedia.org/wiki/Noretynodrel
  3. Norethynodrel. In: Wikidata. https://www.wikidata.org/wiki/Q5659069
  4. Norethynodrel. In: PubChem Compound. CID 6231. https://pubchem.ncbi.nlm.nih.gov/compound/6231