Chemicals and Drugs

Norfenfluramine

A FENFLURAMINE analog that inhibits serotonin uptake and may provoke release of serotonin. It is used as an appetite depressant and an experimental tool in animal studies.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A FENFLURAMINE analog that inhibits serotonin uptake and may provoke release of serotonin. It is used as an appetite depressant and an experimental tool in animal studies.

Chemical Identity

Chemical Information

Molecular Formula
C10H12F3N
Molecular Weight
203.20 g/mol
CAS Registry No.
1886-26-6
IUPAC Name
1-[3-(trifluoromethyl)phenyl]propan-2-amine
InChIKey
MLBHFBKZUPLWBD-UHFFFAOYSA-N
SMILES
CC(CC1=CC(=CC=C1)C(F)(F)F)N
MeSH Unique ID
D009642
Source
PubChem CID 15897

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Dexnorfenfluramine
  • Nordexfenfluramine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under FENFLURAMINE 1975-90

MeSH Record

Previous Indexing

  • Hydrocarbons, Fluorinated (1974)
  • Phenethylamines (1973-1974)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Norfenfluramine. Medical Subject Headings (MeSH). 2026. Unique ID D009642. http://id.nlm.nih.gov/mesh/2026/D009642
  2. Norfenfluramine. In: Wikipedia. https://en.wikipedia.org/wiki/Norfenfluramine
  3. Norfenfluramine. In: Wikidata. https://www.wikidata.org/wiki/Q3069482
  4. Norfenfluramine. In: PubChem Compound. CID 15897. https://pubchem.ncbi.nlm.nih.gov/compound/15897