Chemicals and Drugs

Nortriptyline

A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.

Chemical Identity

Chemical Information

Molecular Formula
C19H21N
Molecular Weight
263.4 g/mol
CAS Registry No.
72-69-5
IUPAC Name
N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine
InChIKey
PHVGLTMQBUFIQQ-UHFFFAOYSA-N
SMILES
CNCCC=C1C2=CC=CC=C2CCC3=CC=CC=C31
MeSH Unique ID
D009661
Source
PubChem CID 4543

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

22 entry terms
  • Desitriptyline
  • Desmethylamitriptylin
  • Allegron
  • Apo-Nortriptyline
  • Aventyl
  • Gen-Nortriptyline
  • Norfenazin
  • Nortrilen
  • Nortriptyline Hydrochloride
  • Novo-Nortriptyline
  • Nu-Nortriptyline
  • PMS-Nortriptyline
  • Pamelor
  • Paxtibi
  • ratio-Nortriptyline
  • Apo Nortriptyline
  • Gen Nortriptyline
  • Hydrochloride, Nortriptyline
  • Novo Nortriptyline
  • Nu Nortriptyline
  • PMS Nortriptyline
  • ratio Nortriptyline

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

68(65)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.847w.181w.384.535w
  2. D04w.615w.181w.384.535w

AMA Style

References

  1. National Library of Medicine. Nortriptyline. Medical Subject Headings (MeSH). 2026. Unique ID D009661. http://id.nlm.nih.gov/mesh/2026/D009661
  2. Nortriptyline. In: Wikipedia. https://en.wikipedia.org/wiki/Nortriptyline
  3. Nortriptyline. In: Wikidata. https://www.wikidata.org/wiki/Q61387
  4. Nortriptyline. In: PubChem Compound. CID 4543. https://pubchem.ncbi.nlm.nih.gov/compound/4543