Chemicals and Drugs

Nucleoside-Diphosphate Kinase

An enzyme that is found in mitochondria and in the soluble cytoplasm of cells. It catalyzes reversible reactions of a nucleoside triphosphate, e.g., ATP, with a nucleoside diphosphate, e.g., UDP, to form ADP and UTP. Many nucleoside diphosphates can act as acceptor, while many ribo- and deoxyribonucleoside triphosphates can act as donor. EC 2.7.4.6.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that is found in mitochondria and in the soluble cytoplasm of cells. It catalyzes reversible reactions of a nucleoside triphosphate, e.g., ATP, with a nucleoside diphosphate, e.g., UDP, to form ADP and UTP. Many nucleoside diphosphates can act as acceptor, while many ribo- and deoxyribonucleoside triphosphates can act as donor. EC 2.7.4.6.

MeSH Record

Classification

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MeSH Record

Synonyms

12 entry terms
  • Deoxynucleoside Diphosphate Kinases
  • Nucleoside Diphosphokinases
  • Nucleoside-Diphosphate Kinases
  • Diphosphate Kinases, Deoxynucleoside
  • Diphosphokinases, Nucleoside
  • Kinase, Nucleoside-Diphosphate
  • Kinases, Deoxynucleoside Diphosphate
  • Kinases, Nucleoside-Diphosphate
  • Nucleoside Diphosphate Kinase
  • Nucleoside Diphosphate Kinases
  • GDP Kinase
  • Kinase, GDP

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

94; was NUCLEOSIDE DIPHOSPHATE KINASES 1977-93 (see under PHOSPHOTRANSFERASES, ATP 1977-90)

MeSH Record

Previous Indexing

  • Nucleotides (1966-1976)
  • Phosphotransferases (1966-1973)
  • Phosphotransferases, ATP (1974-1976)

MeSH Hierarchy

Tree Number

  1. D08.811w.913w.696w.650.550w

AMA Style

References

  1. National Library of Medicine. Nucleoside-Diphosphate Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D009701. http://id.nlm.nih.gov/mesh/2026/D009701
  2. Nucleoside-Diphosphate Kinase. In: Wikipedia. https://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase
  3. Nucleoside-Diphosphate Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q3346048