Structured Summary
Abstract
An enzyme that transfers methyl groups from O(6)-methylguanine, and other methylated moieties of DNA, to a cysteine residue in itself, thus repairing alkylated DNA in a single-step reaction. EC 2.1.1.63.
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Classification
Broader headings
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MeSH Record
Synonyms
11 entry terms
- Guanine-O(6)-Alkyltransferase
- Methylated-DNA-Protein-Cysteine S-Methyltransferase
- O(6)-AGT
- O(6)-Alkylguanine-DNA Alkyltransferase
- O(6)-MeG-DNA Methyltransferase
- O(6)-Methylguanine DNA Transmethylase
- O(6)-Methylguanine Methyltransferase
- Methylated DNA Protein Cysteine S Methyltransferase
- S-Methyltransferase, Methylated-DNA-Protein-Cysteine
- DNA Repair Methyltransferase I
- DNA Repair Methyltransferase II
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
98; use O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE (NM) 1980-97
MeSH Record
Previous Indexing
- DNA (Cytosine-5-)-Methyltransferase (1978-1982)
- Methyltransferases (1978-1997)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. O(6)-Methylguanine-DNA Methyltransferase. Medical Subject Headings (MeSH). 2026. Unique ID D019853. http://id.nlm.nih.gov/mesh/2026/D019853
- O(6)-Methylguanine-DNA Methyltransferase. In: Wikipedia. https://en.wikipedia.org/wiki/Methylated-DNA%E2%80%93protein-cysteine_methyltransferase
- O(6)-Methylguanine-DNA Methyltransferase. In: Wikidata. https://www.wikidata.org/wiki/Q21118735