Diseases

Ochronosis

The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).

MeSH Record

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Broader headings

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MeSH Record

Synonyms

1 entry terms
  • Ochronoses

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Hierarchy

Tree Number

  1. C23.550.744w

AMA Style

References

  1. National Library of Medicine. Ochronosis. Medical Subject Headings (MeSH). 2026. Unique ID D009794. http://id.nlm.nih.gov/mesh/2026/D009794
  2. Ochronosis. In: Wikipedia. https://en.wikipedia.org/wiki/Ochronosis
  3. Ochronosis. In: Wikidata. https://www.wikidata.org/wiki/Q1507609