Chemicals and Drugs

Omalizumab

An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high-affinity IgE receptor binding. It inhibits the binding of IgE to MAST CELLS and BASOPHILS to reduce the severity of the allergic response and is used in the management of persistent allergic ASTHMA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high-affinity IgE receptor binding. It inhibits the binding of IgE to MAST CELLS and BASOPHILS to reduce the severity of the allergic response and is used in the management of persistent allergic ASTHMA.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Xolair

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2016 (2001)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.124w.486.485.114w.071.500w
  2. D12.776w.124w.486.485.114w.224w.060w.844w
  3. D12.776w.124w.790.651.114w.071.500w
  4. D12.776w.124w.790.651.114w.224w.060w.844w
  5. D12.776w.377w.715.548.114w.071.500w
  6. D12.776w.377w.715.548.114w.224w.200w.844w

MeSH Record

NLM Classification

QW 575.5.A6

AMA Style

References

  1. National Library of Medicine. Omalizumab. Medical Subject Headings (MeSH). 2026. Unique ID D000069444. http://id.nlm.nih.gov/mesh/2026/D000069444
  2. Omalizumab. In: Wikipedia. https://en.wikipedia.org/wiki/Omalizumab
  3. Omalizumab. In: Wikidata. https://www.wikidata.org/wiki/Q415392