Chemicals and Drugs

Oncostatin M

A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.

MeSH Record

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Drug Class

Pharmacological Action

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1987)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.276.374w.562w
  2. D12.776w.467.374w.562w
  3. D23.529.374w.562w

AMA Style

References

  1. National Library of Medicine. Oncostatin M. Medical Subject Headings (MeSH). 2026. Unique ID D053683. http://id.nlm.nih.gov/mesh/2026/D053683
  2. Oncostatin M. In: Wikipedia. https://en.wikipedia.org/wiki/Oncostatin_M
  3. Oncostatin M. In: Wikidata. https://www.wikidata.org/wiki/Q909425