Anatomy

Ovarian Follicle

An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS.

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Synonyms

11 entry terms
  • Ovarian Follicles
  • Follicle, Ovarian
  • Follicles, Ovarian
  • Atretic Follicle
  • Graafian Follicle
  • Atretic Follicles
  • Follicle, Atretic
  • Follicle, Graafian
  • Follicles, Atretic
  • Follicles, Graafian
  • Graafian Follicles

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings abnormalities, anatomy & histology, blood supply, chemistry, cytology, diagnostic imaging, drug effects, embryology, enzymology, growth & development, immunology, injuries, innervation, metabolism, microbiology, parasitology, pathology, physiology, physiopathology, radiation effects, surgery, transplantation, ultrastructure, virology.

MeSH Record

Indexing Annotation

/cytol: consider also THECA CELLS; GRANULOSA CELLS; for follicular development use /physiol, not /growth

MeSH Record

History Note

1999

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

WP 320

AMA Style

References

  1. National Library of Medicine. Ovarian Follicle. Medical Subject Headings (MeSH). 2026. Unique ID D006080. http://id.nlm.nih.gov/mesh/2026/D006080
  2. Ovarian Follicle. In: Wikipedia. https://en.wikipedia.org/wiki/Ovarian_follicle
  3. Ovarian Follicle. In: Wikidata. https://www.wikidata.org/wiki/Q953556