Chemicals and Drugs

Oxidopamine

A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.

Chemical Identity

Chemical Information

Molecular Formula
C8H11NO3
Molecular Weight
169.18 g/mol
CAS Registry No.
1199-18-4
IUPAC Name
5-(2-aminoethyl)benzene-1,2,4-triol
InChIKey
DIVDFFZHCJEHGG-UHFFFAOYSA-N
SMILES
C1=C(C(=CC(=C1O)O)O)CCN
MeSH Unique ID
D016627
Source
PubChem CID 4624

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • 6-Hydroxydopamine
  • 6-OHDA
  • 6 Hydroxydopamine
  • Oxidopamine Hydrobromide
  • Oxidopamine Hydrochloride
  • Hydrobromide, Oxidopamine
  • Hydrochloride, Oxidopamine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

92; was 6-HYDROXYDOPAMINE (NM) 1981-91

MeSH Record

Previous Indexing

  • Hydroxydopamines (1973-1991)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Oxidopamine. Medical Subject Headings (MeSH). 2026. Unique ID D016627. http://id.nlm.nih.gov/mesh/2026/D016627
  2. Oxidopamine. In: Wikipedia. https://en.wikipedia.org/wiki/Oxidopamine
  3. Oxidopamine. In: Wikidata. https://www.wikidata.org/wiki/Q780181
  4. Oxidopamine. In: PubChem Compound. CID 4624. https://pubchem.ncbi.nlm.nih.gov/compound/4624