Structured Summary
Abstract
A paired box transcription factor that functions in the development of THYROCYTES and the control of thyroid-specific gene expression. Mutations in the PAX8 gene are associated with THYROID DYSGENESIS and THYROID NEOPLASMS.
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Classification
Broader headings
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MeSH Record
Synonyms
4 entry terms
- Paired-Box Protein, PAX8
- PAX8 Paired-Box Protein
- Paired Box Protein, PAX8
- Transcription Factor, PAX8
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- DNA-Binding Proteins (1993-2016)
- Nuclear Proteins (1993-2016)
- Paired Box Transcription Factors (2006-2016)
- Trans-Activators (1993-2016)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. PAX8 Transcription Factor. Medical Subject Headings (MeSH). 2026. Unique ID D000072636. http://id.nlm.nih.gov/mesh/2026/D000072636
- PAX8 Transcription Factor. In: Wikipedia. https://en.wikipedia.org/wiki/PAX8
- PAX8 Transcription Factor. In: Wikidata. https://www.wikidata.org/wiki/Q21120164