Chemicals and Drugs

PCSK9 Inhibitors

Agents that inhibit Proprotein Convertase Subtilisin/Kexin Type 9 (see PROPROTEIN CONVERTASE 9 (PCSK9)), an enzyme that plays an important role in the degradation of the LDL receptors. It favors LDL catabolism and reduces plasma LDL-cholesterol (LDL_C) level.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Agents that inhibit Proprotein Convertase Subtilisin/Kexin Type 9 (see PROPROTEIN CONVERTASE 9 (PCSK9)), an enzyme that plays an important role in the degradation of the LDL receptors. It favors LDL catabolism and reduces plasma LDL-cholesterol (LDL_C) level.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • PCSK9 Inhibitors Cardiovascular
  • PCSK9 Inhibitors, Cardiovascular
  • Cardiovascular PCSK9 Inhibitors
  • Cardiovascular, PCSK9 Inhibitors
  • Inhibitors, Cardiovascular PCSK9

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2022

MeSH Record

Previous Indexing

  • Anticholesteremic Agents (2018-2021)

MeSH Hierarchy

Tree Numbers

  1. D27.505.519w.186w.071w.202.685
  2. D27.505.519w.389w.745w.800.506
  3. D27.505.954.557.500w.202.685

AMA Style

References

  1. National Library of Medicine. PCSK9 Inhibitors. Medical Subject Headings (MeSH). 2026. Unique ID D000091362. http://id.nlm.nih.gov/mesh/2026/D000091362
  2. PCSK9 Inhibitors. In: Wikidata. https://www.wikidata.org/wiki/Q24228917