Structured Summary
Abstract
A membrane-bound metalloendopeptidase that may play a role in the degradation or activation of a variety of PEPTIDE HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Genetic mutations that result in loss of function of this protein are a cause of HYPOPHOSPHATEMIC RICKETS, X-LINKED DOMINANT.
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Synonyms
6 entry terms
- PEX Phosphate Regulating Neutral Endopeptidase
- Phosphate Regulating Endopeptidase Homolog, X-Linked
- Phosphate Regulating Neutral Endopeptidase
- X-Linked Phosphate Regulating Endopeptidase Homolog
- Phosphate Regulating Endopeptidase Homolog, X Linked
- X Linked Phosphate Regulating Endopeptidase Homolog
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Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2007(1995)
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References
- National Library of Medicine. PHEX Phosphate Regulating Neutral Endopeptidase. Medical Subject Headings (MeSH). 2026. Unique ID D053402. http://id.nlm.nih.gov/mesh/2026/D053402
- PHEX Phosphate Regulating Neutral Endopeptidase. In: Wikidata. https://www.wikidata.org/wiki/Q7119220