Diseases

Palmoplantar Keratoderma

Group of mostly hereditary disorders characterized by thickening of the palms and soles as a result of excessive keratin formation leading to hypertrophy of the stratum corneum (hyperkeratosis).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Group of mostly hereditary disorders characterized by thickening of the palms and soles as a result of excessive keratin formation leading to hypertrophy of the stratum corneum (hyperkeratosis).

MeSH Record

Classification

Broader headings

Narrower headings

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MeSH Record

See Also

MeSH Record

Synonyms

15 entry terms
  • Hyperkeratosis Palmaris et Plantaris
  • Keratoderma, Palmoplantar
  • Keratosis Palmaris et Plantaris
  • Keratosis, Palmoplantar
  • Keratodermas, Palmoplantar
  • Keratoses, Palmoplantar
  • Palmoplantar Keratodermas
  • Palmoplantar Keratoses
  • Palmoplantar Keratosis
  • Keratosis Palmoplantaris Transgradiens of Siemens
  • Mal de Meleda
  • Meleda Disease
  • Disease, Meleda
  • Meleda, Mal de
  • de Meleda, Mal

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

KERATODERMA, PALMOPLANTAR, DIFFUSE is also available; do not confuse entry term HYPERKERATOSIS PALMARIS ET PLANTARIS with POROKERATOSIS PALMARIS ET PLANTARIS DISSEMINATA see POROKERATOSIS

MeSH Record

History Note

93; was KERATOSIS PALMARIS ET PLANTARIS 1974-92; KERATODERMA, PALMOPLANTAR was see KERATOSIS PALMARIS ET PLANTARIS 1990-92

MeSH Hierarchy

Tree Numbers

  1. C16w.320w.850w.475w
  2. C17.800w.428w.435w
  3. C17.800w.827w.475w

MeSH Record

NLM Classification

WR 155

AMA Style

References

  1. National Library of Medicine. Palmoplantar Keratoderma. Medical Subject Headings (MeSH). 2026. Unique ID D007645. http://id.nlm.nih.gov/mesh/2026/D007645
  2. Palmoplantar Keratoderma. In: Wikipedia. https://en.wikipedia.org/wiki/Palmoplantar_keratoderma
  3. Palmoplantar Keratoderma. In: Wikidata. https://www.wikidata.org/wiki/Q7128426