Structured Summary
Abstract
Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
10 entry terms
- Cerebellar Degeneration, Paraneoplastic
- Cerebellar Syndrome, Paraneoplastic
- Paraneoplastic Cerebellar Syndrome
- Cerebellar Syndromes, Paraneoplastic
- Degeneration, Paraneoplastic Cerebellar
- Paraneoplastic Cerebellar Syndromes
- Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration
- Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated
- Anti Yo Associated Paraneoplastic Cerebellar Degeneration
- Paraneoplastic Cerebellar Degeneration, Anti Yo Associated
MeSH Record
Aspects Covered
35 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.
MeSH Record
Indexing Annotation
coord with precoord organ/neopl term + histol type
MeSH Record
History Note
2000
MeSH Record
Previous Indexing
- Cerebellar Ataxia (1975-1999)
- Paraneoplastic Syndromes (1980-1999)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Paraneoplastic Cerebellar Degeneration. Medical Subject Headings (MeSH). 2026. Unique ID D020362. http://id.nlm.nih.gov/mesh/2026/D020362
- Paraneoplastic Cerebellar Degeneration. In: Wikipedia. https://en.wikipedia.org/wiki/Paraneoplastic_cerebellar_degeneration
- Paraneoplastic Cerebellar Degeneration. In: Wikidata. https://www.wikidata.org/wiki/Q3508804